Boyle's novel Budding Prospects was produced as an audiobook in 1994 by Books on Tape.

Boyle's novelDrop City was produced as an audiobook in 2003 by Audio Books Unabridged.

Boyle's novel A Friend of the Earth was produced as an audiobook in 2000 by Books on Tape.

Boyle's novel The Road to Wellville was adapted as a feature film in 1994 by Columbia Pictures. The film, written and directed by Alan Parker, featured an all-star cast, including Anthony Hopkins, Bridget Fonda, Matthew Broderick, John Cusack, and Dana Carvey. It is available on DVD and VHS from Columbia Tristar Home Video.

Boyle's story collection Without a Hero was produced as an audiobook in 1994 by Books on Tape.