Trifles is based on a Glaspell short story entitled "A Jury of Her Peers." A short film version of A Jury of Her Peers was produced in 1981 by Texture Films. The program aired on PBS in 1987.

Another film adaptation of A Jury of Her Peers, entitled An Eye for an Eye, was created by Diana Maddox for the Canadian Broadcasting Corporation's "Guest Stage" television series in 1956.

The Canadian Broadcasting Corporation aired a radio drama version of Trifles, directed by Denis Johnston, in February, 1999.