Is obsession a natural trait in all people? What are you personally obsessed about? Do you have anything in your life that compares to Fawcett's need to find the Lost City of Z?

This question helps the readers think about one of the book's main themes. The book claims to be a tale about obsession; and in making this theme universal and relatable, the reader has a stronger takeaway than the individual experiences of one man. The question offers much to debate.

Does the author's choice to include himself in the book enrich or distract from the tale?

This questions challenges the basic structure of the book. An argument can be made that the author's personal tale is unnecessary to understanding the full picture of Colonel Fawcett; another argument can be made that it creates a sense of closure and validation.

What long-held assumptions about the world do you think need to be challenged, like the ancient civilizations of the Amazon?