Farewell (sweet Cooke-ham) where I first obtain'd / Grace from that Grace where perfit Grace remain'd
-- Speaker (Lines 1 – 2)

Importance: These are the initial lines of the poem. The speaker immediately makes the text's circumstances clear: the poem is being written to say farewell to a place called Cooke-ham. This place is deeply important to the speaker. The next line, with its repetition of the word "grace," is a little harder to gloss. It refers to the speaker's ability to find inspiration, artistic and personal, in her experiences, and also to benefit from the influence of her noble patroness.

Yet you (great Lady) Mistris of that Place, / From whose desires did spring this worke of Grace
-- Speaker (Lines 11 – 12)

Importance: In this line, the speaker addresses Anne Clifford for the first (though certainly not the last) time in the poem. Here, her role is simply that of patroness. She is an important figure, a "great Lady," and identified with...