The Death of Superman is the story of Superman's confrontation with his greatest enemy, the beast called Doomsday. The beast will be unrelenting and single minded. The only hope that Superman has is to give everything he has in order to stop the monster and save those he loves. Superman will have to fight not just for his life, but everyone's lives when Doomsday arrives.

Lois Lane is at the Daily Planet news paper building when she receives an anonymous note telling her to send Superman to a power plant. Lois goes herself and Superman will have to come and save her from a band of hideous creatures that plan on taking over Metropolis.

Superman goes for an interview with a talk show host, Cat Grant. During the interview unbeknown to Superman the members of the Justice League are battling a creature that they soon dub Doomsday. Ice, Blue Beetle, Maxima, Booster, Guy Gardner, and Bloodwynd battle the creature but Doomsday is to strong for them and to quick. Blue Beetle is nearly killed and several others are hurt. Ice goes off to try and slow the creature down while Maxima takes Blue Beetle to the hospital.

Superman shows up shortly after while Doomsday is attacking a home of single mother and her two children. Superman arrives and he and the other members of the Justice League begin to battle the creature again. Many members of the team are already hurt and Guy Gardner can no longer see where to blast because his face is so swollen. The house catches on fire and Superman has to stop his battle for a moment allowing the creature to escape, in order to save the woman that owned the house and her infant. The paramedics arrive and most of the members of the Justice League require medical attention and are taken away. Superman continues to battle the creature and finds that it seems to get stronger the more that Superman fights it. Maxima comes back to fight with Superman for a moment but her apparent lack of concern for the innocent people around puts them all in danger and allows Doomsday to get away for a moment and puts Maxima in the hospital.

The creature is finally able to make it's way to Metropolis. Superman has fought it every step of the way but out of the two only Superman looks to be hurting. Superman is determined to stop the creature. When the beast turns toward Jimmy Olsen and Lois Lane Superman grabs the monster and finds a way to hurt it. In one last final blow both of them fly through the air and Superman has defeated Doomsday. Lois runs to his side and Superman dies in her arms.