"I Have No Mouth, and I Must Scream" was recorded on audiocassette in October 1999 by NewStar Media. The short story was also rendered into a computer game on CD-ROM for Macintosh or PC computers in 1995 by Cyberdreams of Calabasas, California. A companion guide, I Have No Mouth, and I Must Scream: The Official Strategy Guide (1995), was written by Mel Odom and Harlan Ellison and published by Prima Publishing.