Directed by Nicolas Roeg, Heart of Darkness was adapted for television and broadcast on TNT in 1994. The film features Tim Roth as Marlow and John Malkovich as Kurtz, and is available on cassette from Turner Home Entertainment.

The structure of Heart of Darkness was incorporated into Francis Ford Coppola's award-winning 1979 film Apocalypse Now, starring Marlon Brando and Martin Sheen. The insanities presented in the book as stemming from isolation in the African Jungle are in the film transposed to the jungles of Vietnam. Available from Paramount Home Video.

Two sound recordings of Heart of Darkness exist. Both are abridged and produced on two cassettes each. One was recorded by HarperCollins in 1969, is narrated by Anthony Quayle, and runs 91 minutes. The other is a 180-minute recording, published by Penguin-High Bridge audio in 1994, with narration by David Threlfall.