Paramount Pictures released a film version of The Education of Little Tree in 1997.

Earl Richard Friedenberg adapted and directed the novel. The film starred Joseph Aston as Little Tree, James Cromwell as Granpa, and Tantoo Cardinal as Granma.

Readers interested in novels that depict the lives and history of Native Americans may also like Mountain Windsong: A Novel of the Trail of Tears, by Robert J. Conley (reissued 1995), which tells the story of Waguli and Oconeechee, a young Cherokee man and woman separated by the Trail of Tears.

Joseph Bruchac's The Journal of Jesse Smoke, A Cherokee Boy, The Trail of Tears, 1938 (2001) is a sixteen-year-old Cherokee boy's record of the events leading up to the Trail of Tears, as well as the excruciating journey west. It is told in a diary-format novel that comes alive with details of everyday life and of Cherokee spirituality and world...