The United States Office of Research Integrity (ORI) has broad responsibilities for monitoring investigations of misconduct and promoting integrity in research supported by the Public Health Service (PHS). It is administratively located in the Office of Public Health and Science (OPHS) within the Office of the Secretary of Health and Human Services (OS, HHS) and reports to the Secretary of HHS through the Assistant Secretary for Health (ASH). The scope of its responsibilities extends to about four thousand research institutions worldwide. Although separate from the major PHS research funding agencies, such as the National Institutes of Health (NIH), the Centers for Disease Control (CDC), and the Food and Drug Administration (FDA), ORI works with these agencies as well as other government agencies to promote responsible conduct in federally supported research.

Origin and Development

The origins of ORI extend back to the early...