On Saturday, January 16, 1999, two high school girls, Samantha Reid and Melanie Sindone, joined three male seniors for a night out. After finding nothing to do, the seniors drove the girls to the apartment of an older friend in Grosse Isle, Michigan.

There, in what they say was an attempt to liven the party, the young men slipped either GHB or the chemically related GBL into Reid's soft drink and Sindone's alcoholic drink without their knowledge. Within minutes of consuming their drinks, the drug caused both girls to vomit and go into a coma. It wasn't until hours later that they were taken to the hospital. Sindone survived, but her best friend did not. Reid died as a result of vomit blocking air from entering her lungs.

A little more than a year later, the four men were prosecuted in the nation's first GHB-related homicide...