Developed in the late 1970s for use in large-scale studies of the prevalence of mental disorders in the U.S. population (Regier et al., 1984), the Diagnostic Interview Schedule (DIS) is a highly structured psychiatric interview that carefully specifies the questions that the interviewer must ask to make a DIAGNOSIS. Another version is the DISC, or Diagnostic Interview Schedule for Children. Unlike the DIS, this version allows the re-ordering of questions or sections. Because the DIS requires a minimum of clinical judgment, it can be administered by nonprofessional or nonclinician interviewers who have received a week of intensive training. In addition to alcohol and other substance-use disorders, the DIS provides diagnostic information about DEPRESSION, SCHIZOPHRENIA, and ANXIETY disorders; eating disorders; ANTI-SOCIAL PERSONALITY; and a variety of other psychiatric conditions. The DIS has been the subject of a number of validation studies showing that...