Barbiturates - Research Article from Encyclopedia of Drugs, Alcohol & Addictive Behavior

This encyclopedia article consists of approximately 8 pages of information about Barbiturates.

Barbiturates - Research Article from Encyclopedia of Drugs, Alcohol & Addictive Behavior

This encyclopedia article consists of approximately 8 pages of information about Barbiturates.
This section contains 2,288 words
(approx. 8 pages at 300 words per page)
Buy the Barbiturates Encyclopedia Article

Barbiturates refer to a class of general central nervous system depressants that are derived from barbituric acid, a chemical discovered in 1863 by the Nobel Prize winner in chemistry (1905) Adolf von Baeyer (1835-1917). Barbituric acid itself is devoid of central depressant activity; however, German scientists Emil Hermann Fischer and Joseph von Mering made some modifications to its structure and synthesized barbital, which was found to possess depressant properties. Scientists had been looking for a drug to treat anxiety and nervousness but without the dependence-producing effects of OPIATE drugs such as OPIUM, CODEINE, and MORPHINE. Other drugs such as bromide salts, CHLORAL HYDRATE, and paraldehyde were useful sedatives, but they all had problems such as toxicity or they left such a bad taste in patients' mouths that they preferred not to take them. Fischer and von Mering noted that barbital produced sleep in both humans and animals. It was introduced...

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This section contains 2,288 words
(approx. 8 pages at 300 words per page)
Buy the Barbiturates Encyclopedia Article
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Barbiturates from Macmillan. Copyright © 2001-2006 by Macmillan Reference USA, an imprint of the Gale Group. All rights reserved.