Acetaminophen is used to relieve minor aches and pains such as headaches, muscle aches, backaches, toothaches, menstrual cramps, arthritis, and the aches and pains that often accompany colds. It is also used to reduce fever.

Acetaminophen is available without a prescription and is sold under various brand names, including Tylenol, Panadol, Aspirin Free Anacin, and Bayer Select Maximum Strength Headache Pain Relief Formula. Many multi-symptom cold, flu, and sinus medicines also contain acetaminophen.

Studies have shown that acetaminophen relieves pain and reduces fever about as well as aspirin. But differences between these two drugs exist. Acetaminophen is less likely than aspirin to irritate the stomach. However, unlike aspirin, acetaminophen does not reduce the redness, stiffness, or swelling that accompany arthritis.

Acetaminophen has few side effects. The most common one is lightheadedness. Some people experience trembling and pain in the side or the lower back. Allergic reactions are rare...