The river named Woman Hollering Creek forms the center of the borderland in which the story unfolds. It marks the crossings of culture, language, gender, marriage, enslavement, and freedom that take place in the story. Cleofilas's Mexican "town of gossips. . . of dust and despair" on the one side, is not so different from Seguin, Texas, another town of "gossips. .. dust and despair" on the other side, except that in her father's town she is safe from physical harm.