Vivian Bearing is diagnosed with stage four metastatic ovarian cancer. She goes through eight cycles of an aggressive experimental chemotherapy. This treatment is not intended to help Vivian recover; her cancer is too far gone. Instead her treatment will provide much needed research information.
Vivian guides the audience through her tale and shares her reflections with them. The audience follows her journey through her treatment until her ultimate death. Interspersed with this journey, Vivian joins scenes from the far and recent past: when she received her diagnosis; her viewpoint as a student, as a teacher, and a memory of a childhood moment with her father.