What tragic events cause the many inner conflicts from which Isaac Balch needs to heal in the novel, What Comes After?

At the work's onset, Isaac faces the daunting task of moving on after his son's gruesome murder by his next door neighbor-a boy he considered almost as one of his own. Prior to Daniel's death and Jonah's suicide, Isaac's wife Katherine left him for another man. In the wake of this tremendous loss, Isaac tries to navigate how to go on living.