Who was Jules Wendall's one great love in the novel, them?

The one thing Jules wants in life is Nadine Greene, his one great love. Jules becomes infatuated with Nadine the first time he sees her in the driveway of his parents' house. In the novel, he has two relationships with Nadine, one that ends in disappointment (she runs away from him when he is bedridden with the flu) and the other that ends in disaster (she shoots him, then herself).