Medicine as science and an art is a recurring idea. The Medical Detective is replete with examples of illnesses which initially leave medical professionals stymied. Part of the reason for this phenomenon is that a significant number of symptoms suggest a significant variety of illnesses and diseases. The physician is thus faced with a procedure which can best be termed "guess and test," that is, positing a possible diagnosis and then running countless medical and laboratory tests, as well as conducting research and investigation, to confirm or rule out the diagnosis