The novel, which takes place over more than four decades beginning in the early thirties, does not have a permanent setting in the beginning of the novel, but many, many settings as the characters move from town to town. Eventually the narration settles into three prime settings. The first is New York City. It is in New York City that Pookie and her daughters settle shortly before Sarah graduates high school. Later, Emily returns to the city for the remainder of her adult life. Sarah, however, moves to Long Island where she lives with her family for the duration of her marriage. Emily, in the second part of the novel, also lives in Iowa City, Iowa for more than a year.