The feverish desire to own real estate on the part of Eliza in the novel is an indication of what was going on in the town and is a foreshadowing of the last chapters. The book is about the changes that take place in the life of a young man as he goes out into the world, so the unrest in Thomas Wolfe's emotional life may very well reflect the atmosphere of the town he grew up in.
Look Homeward, Angel