In act 2, scene 1 of I Hate Hamlet, the play comes to a climax when Andrew asks John Barrymore for some definitive help in tackling what is considered the most difficult role for the stage, the lead in Hamlet. Rather than write an original response for Barrymore, Rudnick has him repeat the advice that Hamlet gave to actors in the play, using Shakespeare's words from 1601: "Speak the speech, I pray you, as I pronounce it to you," etc. Using this speech in this place works on several different levels. For one thing, it is a sampling from Hamlet, giving Barrymore a chance to show Andrew how to deliver a Shakespearean monologue.