There are various settings for the book. Most of the story takes place in Rosewater County, Indiana where Eliot appears one day after one of his disappearances. It is where many of the family businesses are located. He decides that the local people need help and decides to stay and help them. Indianapolis is also the scene of some of the action since it is where the mental hospital is where first Sylvia and later Eliot are confined.
Rhode Island is also the background from several chapters of action since it is where Fred Rosewater resides in the town of Pisquontuit. The Rhode Island characters are introduced and developed in the second half of the book.
There are other locations in the book. New York City and Washington DC are the sites of some of the action. The Senator lives in Washington DC and his apartment is the site of the meeting regarding the divorce of Sylvia and Eliot. New York is where Sylvia and Eliot live when he takes over the presidency of the Foundation. Other sites are mentioned because of Eliot's wanderings.
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