What is the main conflict in Endgame by Samuel Beckett?

As the play opens, Hamm is dying in a world that seems to be coming to an end. Hamm takes satisfaction in knowing that all of existence may fade to nothing. Hamm is confined to a chair, and throughout the play he discards, reluctantly, the continuing prospects of life: food; painkillers; his servant Clov, on whom he is totally dependent; the pole that enables him to move his wheelchair; and holding the dog, on which he lavishes his affection.