A central theme of Blues for an Alabama Sky is economic hardship. Cleage set her play in 1930, early in the depression. The writers and artists of the Harlem Renaissance, which flourished during the 1920s, were hard hit by the depression because the struggle for economic stability detracted from the time and resources necessary to pursue artistic endeavors. Cleage thus focuses on the unknowns of the Harlem Renaissance, those struggling singers, dancers, and other artists who were so financially devastated by the depression that they were unable to successfully pursue their dreams. The character of Angel, in particular, is sidetracked from her goal of being a blues singer by the meager job opportunities available to her after she is fired from the Cotton Club.