What is the main conflict in Benjamin Franklin: An American Life by Walter Isaacson?

This is a non-fiction account of Benjamin Franklin so there isn't a specific major conflict. Benjamin Franklin: An American Life is an account of the deeds of founding father Benjamin Franklin from his humble beginnings as the apprentice of a printer to his international status as wise sage and practical philosopher. Franklin is always clever and practical. He outshines his brother James the printer, to whom he is apprenticed, and James' jealousy over Benjamin's talent causes him to run away to New York.