In some other points of view the inoculation of this disease appears preferable to the variolous inoculation.

In constitutions predisposed to scrophula, how frequently we see the inoculated smallpox rouse into activity that distressful malady!  This circumstance does not seem to depend on the manner in which the distemper has shewn itself, for it has as frequently happened among those who have had it mildly as when it has appeared in the contrary way.

There are many who, from some peculiarity in the habit, resist the common effects of variolous matter inserted into the skin, and who are in consequence haunted through life with the distressing idea of being insecure from subsequent infection.  A ready mode of dissipating anxiety originating from such a cause must now appear obvious.  And, as we have seen that the constitution may at any time be made to feel the febrile attack of cow-pox, might it not, in many chronic diseases, be introduced into the system, with the probability of affording relief, upon well-known physiological principles?

Although I say the system may at any time be made to feel the febrile attack of cow-pox, yet I have a single instance before me where the virus acted locally only, but it is not in the least probable that the same person would resist the action both of the cow-pox virus and the variolous.

Elizabeth Sarfenet lived as a dairymaid at Newpark farm, in this parish.  All the cows and the servants employed in milking had the cow-pox; but this woman, though she had several sores upon her fingers, felt no tumours in the axillae, nor any general indisposition.  On being afterwards casually exposed to variolous infection, she had the smallpox in a mild way.  Hannah Pick, another of the dairymaids who was a fellow-servant with Elizabeth Sarfenet when the distemper broke out at the farm, was, at the same time, infected; but this young woman had not only sores upon her hands, but felt herself also much indisposed for a day or two.  After this, I made several attempts to give her the smallpox by inoculation, but they all proved fruitless.  From the former case then we see that the animal economy is subject to the same laws in one disease as the other.

The following case, which has very lately occurred, renders it highly probable that not only the heels of the horse, but other parts of the body of that animal, are capable of generating the virus which produces the cow-pox.

An extensive inflammation of the erysipelatous kind appeared without any apparent cause upon the upper part of the thigh of a sucking colt, the property of Mr. Millet, a farmer at Rockhampton, a village near Berkeley.  The inflammation continued several weeks, and at length terminated in the formation of three or four small abscesses.  The inflamed parts were fomented, and dressings were applied by some of the same persons who were employed in milking the cows.  The number of cows milked was twenty-four,