Henri endeavoured to take advantage of the check in the fortunes of his antagonists; he sent Anne de Montmorency to support Gaspard de Coligny, the Admiral of France, in Picardy, and in harmony with Paul IV., instructed Francois, Duc de Guise, to enter Italy to oppose the Duke of Alva.  As of old, the French arms at first carried all before them, and Guise, deeming himself heir to the crown of Naples (for he was the eldest great-grandson of Rene II., titular King of Naples), pushed eagerly forward as far as the Abruzzi.  There he was met and outgeneraled by Alva, who drove him back to Rome, whence he was now recalled by urgent summons to France; for the great disaster of St. Quentin had laid Paris itself open to the assault of an enterprising enemy.  With the departure of Guise from Italy the age of the Italian expeditions comes to an end.  On the northern side of the realm things had gone just as badly.  Philibert of Savoy, commanding for Philip with Spanish and English troops, marched into France as far as to the Somme, and laid siege to St. Quentin, which was bravely defended by Amiral de Coligny.  Anne de Montmorency, coming up to relieve the place, managed his movements so clumsily that he was caught by Count Egmont and the Flemish horse, and, with incredibly small loss to the conquerors, was utterly routed (1557).  Montmorency himself and a crowd of nobles and soldiers were taken; the slaughter was great.  Coligny made a gallant and tenacious stand in the town itself, but at last was overwhelmed, and the place fell.  Terrible as these mishaps were to France, Philip II. was not of a temper to push an advantage vigorously; and while his army lingered, Francois de Guise came swiftly back from Italy; and instead of wasting strength in a doubtful attack on the allies in Picardy, by a sudden stroke of genius he assaulted and took Calais (January, 1558), and swept the English finally off the soil of France.  This unexpected and brilliant blow cheered and solaced the afflicted country, while it finally secured the ascendency of the House of Guise.  The Duke’s brother, the Cardinal de Lorraine, carried all before him in the King’s councils; the Dauphin, betrothed long before, was now married to Mary of Scots; a secret treaty bound the young Queen to bring her kingdom over with her; it was thought that France with Scotland would be at least a match for England joined with Spain.  In the same year, 1558, the French advance along the coast, after they had taken Dunkirk and Nieuport, was finally checked by the brilliant genius of Count Egmont, who defeated them at Gravelinea.  All now began to wish for peace, especially Montmorency, weary of being a prisoner, and anxious to get back to Court, that he might check the fortunes of the Guises; Philip desired it that he might have free hand against heresy.  And so, at Cateau-Cambresis, a peace was made in April, 1559, by which France retained the three bishoprics and Calais, surrendering Thionville,