Early in 1552 Maurice of Saxony struck his great blow at his master in the Tyrol, destroying in an instant all the Emperor’s plans for the suppression of Lutheran opinions, and the reunion of Germany in a Catholic empire; and while Charles V. fled for his life, Henri II. with a splendid army crossed the frontiers of Lorraine. Anne de Montmorency, whose opposition to the war had been overborne by the Guises, who warmly desired to see a French predominance in Lorraine, was sent forward to reduce Metz, and quickly got that important city into his hands; Toul and Verdun soon opened their gates, and were secured in reality, if not in name, to France. Eager to undertake a protectorate of the Rhine, Henri II. tried also to lay hands on Strasburg; the citizens, however, resisted, and he had to withdraw; the same fate befell his troops in an attempt on Spires. Still, Metz and the line of the Vosges mountains formed a splendid acquisition for France. The French army, leaving strong garrisons in Lorraine, withdrew through Luxemburg and the northern frontier; its remaining exploits were few and mean, for the one gleam of good fortune enjoyed by Anne de Montmorency, who was unwise and arrogant, and a most inefficient commander, soon deserted him. Charles V., as soon as he could gather forces, laid siege to Metz, but, after nearly three months of late autumnal operations, was fain to break up and withdraw, baffled and with loss of half his army, across the Rhine. Though some success attended his arms on the northern frontier, it was of no permanent value; the loss of Metz, and the failure in the attempt to take it, proved to the worn-out Emperor that the day of his power and opportunity was past. The conclusions of the Diet of Augsburg in 1555 settled for half a century the struggle between Lutheran and Catholic, but settled it in a way not at all to his mind; for it was the safeguard of princely interests against his plans for an imperial unity. Weary of the losing strife, yearning for ease, ordered by his physicians to withdraw from active life, Charles in the course of 1555 and 1556 resigned all his great lordships and titles, leaving Philip his son to succeed him in Italy, the Netherlands, and Spain, and his brother Ferdinand of Austria to wear in his stead the imperial diadem. These great changes sundered awhile the interests of Austria from those of Spain.