the true sign of the disease, every disease being capable of an infinite number of indications?  How many doubts and controversies have they amongst themselves upon the interpretation of urines? otherwise, whence should the continual debates we see amongst them about the knowledge of the disease proceed? how could we excuse the error they so oft fall into, of taking fox for marten?  In the diseases I have had, though there were ever so little difficulty in the case, I never found three of one opinion:  which I instance, because I love to introduce examples wherein I am myself concerned.

A gentleman at Paris was lately cut for the stone by order of the physicians, in whose bladder, being accordingly so cut, there was found no more stone than in the palm of his hand; and in the same place a bishop, who was my particular friend, having been earnestly pressed by the majority of the physicians whom he consulted, to suffer himself to be cut, to which also, upon their word, I used my interest to persuade him, when he was dead and opened, it appeared that he had no malady but in the kidneys.  They are least excusable for any error in this disease, by reason that it is in some sort palpable; and ’tis thence that I conclude surgery to be much more certain, by reason that it sees and feels what it does, and so goes less upon conjecture; whereas the physicians have no ‘speculum matricis’, by which to examine our brains, lungs, and liver.

Even the very promises of physic are incredible in themselves; for, having to provide against divers and contrary accidents that often afflict us at one and the same time, and that have almost a necessary relation, as the heat of the liver and the coldness of the stomach, they will needs persuade us, that of their ingredients one will heat the stomach and the other will cool the liver:  one has its commission to go directly to the kidneys, nay, even to the bladder, without scattering its operations by the way, and is to retain its power and virtue through all those turns and meanders, even to the place to the service of which it is designed, by its own occult property this will dry-the brain; that will moisten the lungs.  Of all this bundle of things having mixed up a potion, is it not a kind of madness to imagine or to hope that these differing virtues should separate themselves from one another in this mixture and confusion, to perform so many various errands?  I should very much fear that they would either lose or change their tickets, and disturb one another’s quarters.  And who can imagine but that, in this liquid confusion, these faculties must corrupt, confound, and spoil one another?  And is not the danger still more when the making up of this medicine is entrusted to the skill and fidelity of still another, to whose mercy we again abandon our lives?