From that day forward Virginio Orsini began that famous partisan warfare which reduced the country about Rome to the most pathetic desolation the world has ever seen.  During all this time Charles viii was at Lyons, not only uncertain as to the route he ought to take for getting into Italy, but even beginning to reflect a little on the chances and risks of such an expedition.  He had found no sympathy anywhere except with Ludovico Sforza; so it appeared not unlikely that he would have to fight not the kingdom of Naples alone, but the whole of Italy to boot.  In his preparations for war he had spent almost all the money at his disposal; the Lady of Beaujeu and the Duke of Bourbon both condemned his enterprise; Briconnet, who had advised it, did not venture to support it now; at last Charles, more irresolute than ever, had recalled several regiments that had actually started, when Cardinal Giuliano delta Rovere, driven out of Italy by the pope, arrived at Lyons, and presented himself before the king.

The cardinal, full of hatred, full of hope, hastened to Charles, and found him on the point of abandoning that enterprise on which, as Alexander’s enemy, delta Rovere rested his whole expectation of vengeance.  He informed Charles of the quarrelling among his enemies; he showed him that each of them was seeking his own ends—­Piero dei Medici the gratification of his pride, the pope the aggrandisement of his house.  He pointed out that armed fleets were in the ports of Villefranche, Marseilles, and Genoa, and that these armaments would be lost; he reminded him that he had sent Pierre d’Urfe, his grand equerry, on in advance, to have splendid accommodation prepared in the Spinola and Doria palaces.  Lastly, he urged that ridicule and disgrace would fall on him from every side if he renounced an enterprise so loudly vaunted beforehand, for whose successful execution, moreover, he had been obliged to sign three treaties of peace that were all vexatious enough, viz. with Henry VII, with Maximilian, and with Ferdinand the Catholic.  Giuliano della Rovere had exercised true insight in probing the vanity of the young king, and Charles did not hesitate for a single moment.  He ordered his cousin, the Duke of Orleans (who later on became Louis XII) to take command of the French fleet and bring it to Genoa; he despatched a courier to Antoine de Bessay, Baron de Tricastel, bidding him take to Asti the 2000 Swiss foot-soldiers he had levied in the cantons; lastly, he started himself from Vienne, in Dauphine, on the 23rd of August, 1494, crossed the Alps by Mont Genevre, without encountering a single body of troops to dispute his passage, descended into Piedmont and Monferrato, both just then governed by women regents, the sovereigns of both principalities being children, Charles John Aime and William John, aged respectively six and eight.