His published correspondence shows that many noted people were in communication with him as his patients.  Roger Williams wants a little of his medicine for Mrs. Weekes’s daughter; worshipful John Haynes is in receipt of his powders; troublesome Captain Underhill wants “a little white vitterall” for his wife, and something to cure his wife’s friend’s neuralgia, (I think his wife’s friend’s husband had a little rather have had it sent by the hands of Mrs. Underhill, than by those of the gallant and discursive captain); and pious John Davenport says, his wife “tooke but one halfe of one of the papers” (which probably contained the medicine he called rubila), “but could not beare the taste of it, and is discouraged from taking any more;” and honored William Leete asks for more powders for his “poore little daughter Graciana,” though he found it “hard to make her take it,” delicate, and of course sensitive, child as she was, languishing and dying before her time, in spite of all the bitter things she swallowed,—­God help all little children in the hands of dosing doctors and howling dervishes!  Restless Samuel Gorton, now tamed by the burden of fourscore and two years, writes so touching an account of his infirmities, and expresses such overflowing gratitude for the relief he has obtained from the Governor’s prescriptions, wondering how “a thing so little in quantity, so little in sent, so little in taste, and so little to sence in operation, should beget and bring forth such efects,” that we repent our hasty exclamation, and bless the memory of the good Governor, who gave relief to the worn-out frame of our long-departed brother, the sturdy old heretic of Rhode Island.

What was that medicine which so frequently occurs in the printed letters under the name of “rubila”?  It is evidently a secret remedy, and, so far as I know, has not yet been made out.  I had almost given it up in despair, when I found what appears to be a key to the mystery.  In the vast multitude of prescriptions contained in the manuscripts, most of them written in symbols, I find one which I thus interpret: 

“Four grains of (diaphoretic) antimony, with twenty grains of nitre, with a little salt of tin, making rubila.”  Perhaps something was added to redden the powder, as he constantly speaks of “rubifying” or “viridating” his prescriptions; a very common practice of prescribers, when their powders look a little too much like plain salt or sugar.

Waitstill Winthrop, the Governor’s son, “was a skilful physician,” says Mr. Sewall, in his funeral sermon; “and generously gave, not only his advice, but also his Medicines, for the healing of the Sick, which, by the Blessing of God, were made successful for the recovery of many.”  “His son John, a member of the Royal Society, speaks of himself as ’Dr. Winthrop,’ and mentions one of his own prescriptions in a letter to Cotton Mather.”  Our President tells me that there was an heirloom of the ancient skill in his family, within his own remembrance, in the form of a certain precious eye-water, to which the late President John Quincy Adams ascribed rare virtue, and which he used to obtain from the possessor of the ancient recipe.