At this time, Genoa withdrew from the dominion of Milan, under the following circumstances. Galeazzo, at his death, left a son, Giovan Galeazzo, who being too young to undertake the government, dissensions arose between Sforza, Lodovico, Ottaviano, and Ascanio, his uncles, and the lady Bona, his mother, each of whom desired the guardianship of the young duke. By the advice and mediation of Tommaso Soderini, who was then Florentine ambassador at the court of Milan, and of Cecco Simonetta, who had been secretary to Galeazzo, the lady Bona prevailed. The uncles fled, Ottaviano was drowned in crossing the Adda; the rest were banished to various places, together with Roberto da San Severino, who in these disputes had deserted the duchess and joined the uncles of the duke. The troubles in Tuscany, which immediately followed, gave these princes hope that the new state of things would present opportunities for their advantage; they therefore quitted the places to which their exile limited them, and each endeavored to return home. King Ferrando, finding the Florentines had obtained assistance from none but the Milanese, took occasion to give the duchess so much occupation in her own government, as to render her unable to contribute to their assistance. By means of Prospero Adorno, the Signor Roberto, and the rebellious uncles of the duke, he caused Genoa to throw off the Milanese yoke. The Castelletto was the only place left; confiding in which, the duchess sent a strong force to recover the city, but it was routed by the enemy; and perceiving the danger which might arise to her son and herself if the war were continued, Tuscany being in confusion, and the Florentines, in whom alone she had hope, themselves