At this time, Pope Pius II. having settled the affairs of Romagna, and witnessing a universal peace, thought it a suitable opportunity to lead the Christians against the Turks, and adopted measures similar to those which his predecessors had used.  All the princes promised assistance either in men or money; while Matthias, king of Hungary, and Charles, duke of Burgundy, intimated their intention of joining the enterprise in person, and were by the pope appointed leaders of the expedition.  The pontiff was so full of expectation, that he left Rome and proceeded to Ancona, where it had been arranged that the whole army should be assembled, and the Venetians engaged to send ships thither to convey the forces to Sclavonia.  Upon the arrival of the pope in that city, there was soon such a concourse of people, that in a few days all the provisions it contained, or that could be procured from the neighborhood, were consumed, and famine began to impend.  Besides this, there was no money to provide those who were in want of it, nor arms to furnish such as were without them.  Neither Matthias nor Charles made their appearance.  The Venetians sent a captain with some galleys, but rather for ostentation and the sake of keeping their word, than for the purpose of conveying troops.  During this position of affairs, the pope, being old and infirm, died, and the assembled troops returned to their homes.  The death of the pontiff occurred in 1465, and Paul II. of Venetian origin, was chosen to succeed him; and that nearly all the principalities of Italy might change their rulers about the same period, in the following year Francesco Sforza, duke of Milan, also died, having occupied the dukedom sixteen years, and Galleazzo, his son, succeeded him.

The death of this prince infused redoubled energy into the Florentine dissensions, and caused them to produce more prompt effects than they would otherwise have done.  Upon the demise of Cosmo, his son Piero, being heir to the wealth and government of his father, called to his assistance Diotisalvi Neroni, a man of great influence and the highest reputation, in whom Cosmo reposed so much confidence that just before his death he recommended Piero to be wholly guided by him, both with regard to the government of the city and the management of his fortune.  Piero acquired Diotisalvi with the opinion Cosmo entertained of him, and said that as he wished to obey his father, though now no more, as he always had while alive, he should consult him concerning both his patrimony and the city.  Beginning with his private affairs, he caused an account of all his property, liabilities, and assets, to be placed in Diotisalvi’s hands, that, with an entire acquaintance with the state of his affairs, he might be able to afford suitable advice, and the latter promised to use the utmost care.  Upon examination of these accounts the affairs were found to be in great disorder, and Diotisalvi, instigated rather by his own ambition than by attachment to Piero