From Antigonus Phoenicia passed to his son Demetrius, who maintained his hold on it, with some vicissitudes of fortune, till B.C. 287, when it once more passed under the dominion of Ptolemy Lagi.[14441] From this time it was an Egyptian dependency for nearly seventy years, and flourished commercially, if it not distinguish itself by warlike exploits. The early Ptolemies were mild and wise rulers. They encouraged commerce, literature, and art. So far as was possible they protected their dominions from external attack, put down brigandage, and ruled with equity and moderation. It was not until the fourth prince of the house of Lagus, Philopator, mounted the throne (B.C. 222) that the character of their rule changed for the worse, and their subjects began to have reason to complain of them. The weakness and profligacy of Philopater[14442] tempted Antiochus III. to assume the aggressive, and to disturb the peace which had now for some time subsisted between Syria and Egypt, the Lagidae and the Seleucidae. In B.C. 219 he drove the Egyptians out of Seleucia, the port of Antioch,[14443] and being joined by Theodotus, the Egyptian governor of the Coelesyrian province, invaded that country and Phoenicia, took possession of Tyre and Accho, which was now called Ptolemais, and threatened Egypt with subjugation.[14444] Phoenicia once more became the battle-field between two great powers, and for the next twenty years the cities were frequently taken and re-taken. At last, in B.C. 198, by the victory of Antiochus over Scopas,[14445] and the surrender of Sidon, Phoenicia passed, with Coelesyria, into the permanent possession of the Seleucidae, and, though frequently reclaimed by Egypt, was never recovered.