De Beriot became identified with the Royal Conservatory of Music at Brussels in the year 1840, and thenceforward his life was devoted to composition and the direction of the violin school. He gave much time and care to the education of his son Charles, who, in addition to a wonderful resemblance to his mother, appears to have inherited much of the musical endowment of both parents. Had not an ample fortune rendered professional labor unnecessary, it is probable that the son of Malibran and De Beriot would have attained a musical eminence worthy of his lineage; but he is even now celebrated for his admirable performances in private, and his musical evenings are said to be among the most delightful entertainments in Parisian society, gathering the most celebrated artists and litterateurs of the great capital.
De Beriot ceased giving public concerts after taking charge of the violin classes of the Brussels Conservatoire, though he continued to charm select audiences in private concerts. Many of his pupils became distinguished players, among whom may be named Monasterio, Standish, Lauterbach, and, chief of all, Henri Vieuxtemps, with whose precocious talents he was so much pleased that he gave him lessons gratuitously. During his life at Brussels, and indeed during the whole of his career, De Beriot enjoyed the friendship and esteem of many of the most distinguished men of the day, among his most intimate friends and admirers having been Prince de Chimay, the Russian Prince Youssoupoff, and King Leopold I, of Belgium. The latter part of his life was not un-laborious in composition, but otherwise of affluent and elegant ease. During the last two years his eyesight failed him, and he gradually became totally blind. He died, April 13, 1870, at the age of sixty-eight, while visiting his friend Prince Youssoupoff at St. Petersburg, of the brain malady which had long been making fatal inroads on his health.