Encouraged by their success in that instance, the intolerant party began furious attacks upon her, one monk going so far as to say from the pulpit that she should be put into a sack and thrown into the Seine.  Upon her publication of a religious poem, Miroir de l’ame pecheresse, in which she failed to mention purgatory or the saints, she was vigorously attacked by Beda, who had the verses condemned by the Sorbonne and caused the pupils of the College of Navarre to perform a morality in which Marguerite was represented under the character of a woman quitting her distaff for a French translation of the Gospels presented to her by a Fury.  This was too much even for Francis, and he ordered the principal and his actors arrested; it was then that Marguerite showed her gentleness, mercy, and humanity by throwing herself at her brother’s feet and asking for their pardon.

After but a short respite the persecution broke out anew, and with the full sanction of the king, who, upon finding at his door a placard against the mass, went even so far as to sign letters patent ordering the suppression of printing (1535).  While away from the soothing influence of his sister, Francis I. was easily persuaded to sign, for the Catholic party, any permit of execution or cruelty.  The life of Marguerite herself was constantly in danger, but in spite of persistent efforts to turn brother against sister, the king continued to protect and defend the latter; and though she gradually drew closer to Catholicism, she continued to protect the Protestants.  She founded nunneries and showed a profound devotion toward the Virgin; although realizing the dangers and follies of the new doctrine, she had too much humanity to encourage cruelty.

The husband whom the king forced upon her was twelve years her junior, poor, and subsidized by Francis; by him she had a daughter, Jeanne d’Albret, who became the champion of Protestantism.  Her married life at Pau, where she had erected beautiful buildings and magnificent terraces, was not happy; the subjects of love that formerly had amused her had lost their charm; and the incurable disease with which her brother was stricken caused her constant worry and mental suffering.  When banquets, the chase, and other amusements no longer attracted Francis, he summoned Marguerite to comfort and console him; her devotion and goodness never failed.  Unable to recover from the grief caused by his death in 1547, she expressed her sorrow in the most beautiful poems.

She gave the remainder of her life to religion and charity, abandoning her literary ambitions and plans.  “The life after death gave her much trouble and many moments of perplexity and uneasiness.  She survived her brother only two years, dying in 1549; the helper and protector of good literature, the defence, consolation, and shelter of the distressed, she was mourned by all France more than was any other queen.”  Sainte-Marthe says:  “How many widows are there, how many orphans, how many afflicted, how many old persons, whom she pensioned every year, who now, like sheep whose shepherd is dead, wander hither and thither, seeking to whom to go, crying in the ears of the wealthy and deploring their miserable fate!” Poets, scholars, all learned and professional men, commemorated their protectress in poems and funeral orations.  France was one large family in deep mourning.