Protoplasm, with which the simplest manifestations of life are associated, was not a compound, but a structure built up of compounds. The chemist might successfully synthesize any of its component molecules, but he had no more reason to look forward to the synthetic production of the structure than to imagine that the synthesis of gallic acid led to the artificial production of gall nuts. Although there was thus no prospect of effecting a synthesis of organized material, yet the progress made in our knowledge of the chemistry of life during the last fifty years had been very great, so much so indeed that the sciences of physiological and of pathological chemistry might be said to have entirely arisen within that period.
CHEMISTRY OF VITAL FUNCTIONS.
He would now briefly trace a few of the more important steps which had marked the recent study of the relations between the vital phenomena and those of the inorganic world. No portion of the science of chemistry was of greater interest or greater complexity than that which, bearing on the vital functions both of plants and of animals, endeavored to unravel the tangled skein of the chemistry of life, and to explain the principles according to which our bodies live, and move, and have their being. If, therefore, in the less complicated problems with which other portions of our science have to deal, we found ourselves often far from possessing satisfactory solutions, we could not be surprised to learn that with regard to the chemistry of the living body—whether vegetable or animal—in health or disease, we were still farther from a complete knowledge of phenomena, even those of fundamental importance.
Liebig asked if we could distinguish, on the one hand, between the kind of food which goes to create warmth and, on the other, that by the oxidation of which the motions and mechanical energy of the body are kept up. He thought he was able to do this, and he divided food into two categories. The starchy or carbo-hydrate food was that, said he, which by its combustion provided the warmth necessary for the existence and life of the body. The albuminous or nitrogenous constituents of our food, the flesh meat, the gluten, the casein out of which our muscles are built up, were not available for the purpose of creating warmth, but it was by the waste of those muscles that the mechanical energy, the activity, the motions of the animal are supplied.
Soon after the promulgation of these views, J.R. Mayer warmly attacked them, throwing out the hypothesis that all muscular action is due to the combustion of food, and not to the destruction of muscle.