This I found by this Experiment, I had a very convenient Microscope with a single Glass which drew about half an Inch, this I had fastned into a little frame, almost like a pair of Spectacles, which I placed before mine eyes, and so holding the leaf of a Nettle at a convenient distance from my eye, I did first, with the thrusting of several of these bristles into my skin, perceive that presently after I had thrust them in I felt the burning pain begin; next I observ’d in divers of them, that upon thrusting my finger against their tops, the Bodkin (if I may so call it) did not in the least bend, but I could perceive moving up and down within it a certain liquor, which upon thrusting the Bodkin against its basis, or bagg B, I could perceive to rise towards the top, and upon taking away my hand, I could see it again subside, and shrink into the bagg; this I did very often, and saw this Phaenomenon as plain as I could ever see a parcel of water ascend and descend in a pipe of Glass.  But the basis underneath these Bodkins on which they were fast, were made of a more pliable substance, and looked almost like a little bagg of green Leather, or rather resembled the shape and surface of a wilde Cucumber, or cucumeris asinini, and I could plainly perceive them to be certain little baggs, bladders, or receptacles full of water, or as I ghess, the liquor of the Plant, which was poisonous, and those small Bodkins were but the Syringe-pipes, or Glyster-pipes, which first made way into the skin, and then served to convey that poisonous juice, upon the pressing of those little baggs, into the interior and sensible parts of the skin, which being so discharg’d, does corrode, or, as it were, burn that part of the skin it touches; and this pain will sometimes last very long, according as the impression is made deeper or stronger.

The other parts of the leaf or surface of the Nettle, have very little considerable, but what is common to most of these kinds of Plants, as the ruggedness or indenting, and hairiness, and other roughnesses of the surface or out-side of the Plant, of which I may say more in another place.  As I shall likewise of certain little pretty cleer Balls or Apples which I have observed to stick to the sides of these leaves, both on the upper and under side, very much like the small Apples which I have often observ’d to grow on the leaves of an Oak call’d Oak-apples which are nothing but the Matrices of an Infect, as I elsewhere shew.

The chief thing therefore is, how this Plant comes, by so slight a touch, to create so great a pain; and the reason of this seems to be nothing else, but the corrosive penetrant liquor contain’d in the small baggs or bladders, upon which grow out those sharp Syringe-pipes, as I before noted; and very consonant to this, is the reason of the pain created by the sting of a Bee, Wasp, &c. as I elsewhere shew:  For by the Dart, which is likewise a pipe, is made a deep