In the campaign of the following year, 1559, numerous battles were fought between the two armies, with various successes; but as these produced no material change in the state of affairs, it is unnecessary to give any particular account of them.  Though several of these encounters ended in favour of the Araucanians, yet Caupolican resolved to protract the war, as his troops were daily diminishing in numbers from being continually exposed to the fire arms of their enemies, while the Spaniards were constantly receiving recruits from Peru and Europe.  With this intention, therefore, he took possession of a strong situation between Canete and Conception, in a place called Quipeo or Cuyapu, which he fortified so strongly as to be defensible by a few men against any number of enemies unprovided with artillery.  On being informed of this measure, Don Garcia marched thither immediately with his army in order to dislodge the Araucanian general, but observing the strength of the position, he delayed for some time making an attack, in hope of drawing the enemy from their strong ground, so that his cavalry might have an opportunity of acting to advantage.  In the mean time, frequent skirmishes took place between the two armies, in one of which the celebrated Millalauco was taken prisoner, and who reproached Don Garcia so severely for his cruel manner of making war, that he ordered him instantly to be impaled.  While the Araucanians were thus blockaded in their intrenched camp, the traitor Andrew had the temerity to go one day with a message from Don Garcia to Caupolican, threatening him with the most cruel punishment if he did not immediately submit to the authority of the Spaniards.  Caupolican, though much enraged at seeing before him the man who had betrayed his father, ordered him immediately to retire, saying that he would assuredly have put him to death by the most cruel tortures, if he had not been invested with the character of an ambassador.  Yet Andrew ventured next day to come into the Araucanian camp as a spy, when he was taken prisoner, suspended by his feet from a tree, and suffocated with smoke.

At length Don Garcia commenced his attack upon the camp of the Araucanians, by a violent cannonade from all his artillery.  Caupolican and his valiant followers made a vigorous sally, and attacked the Spaniards with so much fury as to kill about forty of them at the first charge, and continued the battle for some time with much success.  After a short time, Don Garcia, by a skilful evolution, cut off the retreat of the Araucanians and surrounded them on every side.  Yet Caupolican and his intrepid soldiers fought with such desperate valour that the issue of the engagement remained doubtful for six hours; till, seeing Tucapel, Colocolo, Rencu, Lincoyan, Mariantu, Ongolmo, and several others of his most valiant officers slain, Caupolican attempted to retreat with the small remnant of his army:  But, being overtaken by a party of horse from which he could not possibly escape, he slew himself to avoid a similar, cruel fate as that which his father had endured.