In 1554 Don Alfonso de Noronha was superseded in the government of Portuguese India by Don Pedro de Mascarenhas, who was 70 years of age when appointed viceroy.  Soon after his arrival at Goa, some of the great subjects of Adel Khan, king of Visiapour, made proposals for raising Meale Khan, who had long resided at Goa, to the musnud, and offered to cede the Concan to the crown of Portugal, in reward for assistance in bringing about that revolution.  That province, which produced a million of yearly revenue, was so great a bait, that the enterprise was engaged in without consideration of its difficulties.  Meale Khan was immediately proclaimed king of Visiapour, and a force of 3000 Portuguese infantry with 200 horse and a body of Malabars and Canarins was immediately sent to reduce the fort of Ponda; after which, leaving his family in Goa as hostages for the faithful performance of the treaty, Meale Khan was conducted thither by the viceroy and placed at the head of his new subjects.  Leaving Ponda under the charge of Don Antonio de Noronha, with a garrison of 600 men, the viceroy returned to Goa, where he soon afterwards died, having enjoyed the viceroyalty of India only ten months.

On the death of Mascarenhas, which happened some time in 1555, Francisco de Barreto succeeded to the government by virtue of a patent of succession.  He immediately proceeded to Ponda to support the cause of Meale Khan, who was soon afterwards taken prisoner, and the Portuguese were utterly disappointed in the hopes of profiting by this intended revolution.

In the beginning of 1556, Juan Peixoto sailed with two gallies for the Red Sea, to examine if the Turks were making any preparations at Suez for attacking the Portuguese in India.  Finding every thing quiet, he landed unperceived during the night in the island of Swakem, whence he carried off a considerable booty and many prisoners, and returned to Goa with much honour.

About this time the king of Sinde sent an embassy to the governor general, desiring assistance in a war against one of his neighbours, and 700 men were dispatched for that purpose in 28 vessels under the command of Pedro Barreto, who arrived safe at Tatta in the delta of the Indus, the residence of the king of Sinde.  The prince immediately visited the Portuguese commander, and sent notice of his arrival to the king his father who was absent in the field against the enemy.  As the king made peace with his enemy, Barreto desired leave to depart, and required that the Portuguese should be reimbursed for the expences of the expedition, as had been agreed upon, by the ambassador who solicited it.  Receiving an unsatisfactory answer, Baretto landed his men and entered the city, where he slew above 8000 persons, destroyed to the value of above eight millions in gold[372], and loaded his vessels with the richest booty that had ever been made in India, without losing a single man.  He afterwards spent eight days destroying every thing