Hearing in 1546 that the king of Cambaya intended again to besiege Diu with a larger army than ever, Don Juan de Castro prepared with all diligence to relieve it, borrowing money from the city of Goa for the expences of the expedition; and on this occasion the women of Goa sent him their jewels by the hands of their young daughters, complaining that he had not used them before, and requesting him to do so now; but he sent all back accompanied with presents.  Having fitted out 160 sail of various kinds of vessels with a large military force, Don Juan sailed for Basseen and thence to Surat, where Don Alvaro had arrived before the fleet, and had taken a work with several cannon from the Moors.  Sailing thence to Baroch, the army of the king of Cambaya was seen covering the whole plain, to the amount of 150,000 men, with 80 large cannon in front.  Don John was anxious to land with his small army of 3000 men to give battle to the king, but was dissuaded from the rash attempt by his most experienced officers.  He went on therefore to Diu, where he appointed Luis Falcam to command the castle, as Mascarenhas was then about to return to Portugal.  After this he went along the coast of the Guzerat dominions, landing in many places, and destroying every thing with fire and sword.  The strong and beautiful cities of Pate and Patane, being abandoned by the inhabitants, were utterly destroyed; two hundred vessels were destroyed in their ports, and a prodigious booty was obtained.  Dabul also, though in the dominions of Adel Khan, was treated in a similar manner, in revenge for the ravages committed by the orders of that sovereign in the districts of Salsete and Bardes, which were occupied by Calabate Khan at the head of 20,000 men.

As Calabate Khan seemed disposed to retain possession of these districts, Don Juan went against him with 1500 horse and 4000 foot; but the enemy fled in all haste to the gauts, leaving their tents and baggage behind.  The Portuguese army pursued; and being resisted by Calabate Khan in person, with 2000 horse at a ford or pass, that general was unhorsed and slain by a Portuguese officer named Almeyda, after which the enemy were defeated with great slaughter.  The cymeter, dagger, chain, and rings of the slain general were estimated at the value of 80,000 crowns.  After this victory, Don Juan ravaged the whole country below the gauts belonging to Adel Khan, destroying every thing before him, burning all the towns and woods, and carrying off the cattle and provisions.  From this destructive expedition he returned to Goa, which he again entered in triumph.