N.B.  The case alluded to, in the last of the above replies, was, in the first instance, papular eruption; the base of each papula being surrounded by an inflamed ring; the eruption was thickest on the thorax, and on the arms; in its progress, the eruption became pustular, the pustules being in circumference about half the usual size of the vaccine vesicle; on the twelfth day, the crusts had dropped from some of the smaller pustules; and, by the seventeenth day, they had all dropped off, leaving a mark, but not in any manner pitted; and which, I think, promises to be permanent.

  W.F.

Thursday, October 4th, 1827.—­At length the day arrived when I was to quit Sierra Leone, and I might say with some regret; for, during my residence there, I had been very hospitably and agreeably entertained by the principal government officers, as well as by several of the most respectable merchants; and I had found a sufficient variety of objects of interest, to yield ample occupation for the mind.  I could have desired to remain sometime longer, particularly as the fine weather, and what is called the healthy season, was fast coming on, which would have afforded me more time to examine and reflect on what was of interest to the colony as well as to the mother country; but I was conscious of a feeling of still deeper regret, and of a different character from that of mere curiosity;—­it was the pain of parting from those whose kind sympathy had led them to take more than a common interest in my pursuits, and to whose friendly and constant attentions I was indebted for the advantages I enjoyed while I remained in the colony.

The apprehension, too, which was afterwards fatally realized, that many of us should never meet again, was calculated to embitter my leave-taking, even more poignantly.  Of the friends who were then around me at Sierra Leone, the greater number are now no more; the principal persons amongst whom are the following:  Colonels Lumley and Denham; Mr. K. Macauley (member of council); Mr. Barber, Mr. Leavers, Mr. Reffel (acting judge), Mr. Magnus (clerk of the court), Lieutenant Green, R.A.C., and several gentlemen volunteers of the same corps.

At daylight in the morning, just as the ship was preparing to get her anchors up, a heavy tornado came on, and the rain continued for some hours after the violence of the wind had subsided.  Notwithstanding the rain, however, Colonel Lumley, the Lieutenant-Governor of the colony, and his private secretary.  Lieutenant McLean, R.A.C., came on board at eight o’clock for a passage to Cape Coast, where the Lieutenant-Governor was going for the purpose of delivering the fortress of Cape Coast Castle into the hands of the British merchants, who were to take possession of it with a militia force, which they were permitted to organize for their own protection:  the Government allowing them a stipulated sum to support the necessary establishment, at the same time withdrawing the troops of the Royal African Corps, and all the government stores, part of which were to be sent to Fernando Po, and the rest to Sierra Leone or England.