This is difficult. There exists no proof, I believe, that the effigies of the Virgin with the infant Christ in her arms, which existed before the end of the fifth century, were placed before Christian worshippers as objects of veneration. They appear to have been merely groups representing a particular incident of the New Testament, namely, the adoration of the Magi; for I find no other in which the mother is seated with the infant Christ, and this is an historical subject of which we shall have to speak hereafter. From the beginning of the fourth century, that is, from the time of Constantine and the condemnation of Arius, the popular reverence for the Virgin, the Mother of Christ, had been gaining ground; and at the same time the introduction of images and pictures into the places of worship and into the houses of Christians, as ornaments on glass vessels and even embroidered on garments and curtains, became more and more diffused, (v. Neander’s Church History.)
The earliest effigies of the Virgin and Child may be traced to Alexandria, and to Egyptian influences; and it is as easily conceivable that the time-consecrated Egyptian myth of Isis and Horus may have suggested the original type, the outward form and the arrangement of the maternal group, as that the classical Greek types of the Orpheus and Apollo should have furnished the early symbols of the Redeemer as the Good Shepherd; a fact which does not rest upon supposition, but of which the proofs remain to us in the antique Christian sculptures and the paintings in the catacombs.
The most ancient Greek figures of the Virgin and Child have perished; but, as far as I can learn, there is no evidence that these effigies were recognized by the Church as sacred before the beginning of the sixth century. It was the Nestorian schism which first gave to the group of the Mother bearing her divine Son that religious importance and significance which it has ever since retained in Catholic countries.