It was not only from considerations of external policy, and in order to conciliate to himself Emperor Maximilian and King Ferdinand, that Louis XII. had allowed himself to proceed to concessions so plainly contrary to the greatest interests of France:  he had yielded also to domestic influences.  The queen his wife, Anne of Brittany, detested Louise of Savoy, widow of Charles d’Orleans, Count of Angouleme, and mother of Francis d’Angouleme, heir presumptive to the throne, since Louis XII. had no son.  Anne could not bear the idea that her daughter, Princess Claude, should marry the son of her personal enemy; and, being more Breton than French, say her contemporaries, she, in order to avoid this disagreeableness, had used with the king all her influence, which was great, in favor of the Austrian marriage, caring little, and, perhaps, even desiring, that Brittany should be again severed from France.  Louis, in the midst of the reverses of his diplomacy, had thus to suffer from the hatreds of his wife, the observations of his advisers, and the reproaches of his conscience as a king.  He fell so ill that he was supposed to be past recovery.  “It were to do what would be incredible,” says his contemporary, John de St. Gelais, “to write or tell of the lamentations made throughout the whole realm of France, by reason of the sorrow felt by all for the illness of their good king.  There were to be seen night and day, at Blois, at Amboise, at Tours, and everywhere else, men and women going all bare throughout the churches and to the holy places, in order to obtain from divine mercy grace of health and convalescence for one whom there was as great fear of losing as if he had been the father of each.”  Louis was touched by this popular sympathy; and his wisest councillors, Cardinal d’Amboise the first of all, took advantage thereof to appeal to his conscience in respect of the engagements which “through weakness he had undertaken contrary to the interests of the realm and the coronation-promises.”  Queen Anne herself, not without a struggle, however, at last gave up her opposition to this patriotic recoil; and on the 10th of May, 1505, Louis XII. put in his will a clause to the effect that his daughter, Princess Claude, should be married, so soon as she was old enough, to the heir to the throne, Francis, Count of Angouleme.  Only it was agreed, in order to avoid diplomatic embarrassments, that this arrangement should be kept secret till further notice. [The will itself of Louis XII. has been inserted in the Recueil des Ordonnances des Bois des France, t. xxi. p. 323, dated 30th of May, 1505.]