The persecution of the Christians did not stop at Lyons, or with Marcus Aurelius; it became, during the third century, the common practice of the emperors in all parts of the Empire:  from A.D. 202 to 312, under the reigns of Septimius Severus, Maximinus the First, Decius, Valerian, Aurelian, Diocletian, Maximian, and Galerius, there are reckoned six great general persecutions, without counting others more circumscribed or less severe.  The Emperors Alexander Severns, Philip the Arabian, and Constantius Chlorus were almost the only exceptions to this cruel system; and nearly always, wherever it was in force, the Pagan mob, in its brutality or fanatical superstition, added to imperial rigor its own atrocious and cynical excesses.

But Christian zeal was superior in perseverance and efficacy to Pagan persecution.  St. Pothinus the Martyr was succeeded as bishop at Lyons by St. Irenaeus, the most learned, most judicious, and most illustrious of the early heads of the Church in Gaul.  Originally from Asia Minor, probably from Smyrna, he had migrated to Gaul, at what particular date is not known, and had settled as a simple priest in the diocese of Lyons, where it was not long before he exercised vast influence, as well on the spot as also during certain missions intrusted to him, and amongst them one, they say, to the Pope St. Eleutherius at Rome.  Whilst Bishop of Lyons, from A.D. 177 to 202, he employed the five and twenty years in propagating the Christian faith in Gaul, and in defending, by his writings, the Christian doctrines against the discord to which they had already been subjected in the East, and which was beginning to penetrate to the West.  In 202, during the persecution instituted by Septimius Severus, St. Irenaeus crowned by martyrdom his active and influential life.  It was in his episcopate that there began what may be called the swarm of Christian missionaries who, towards the end of the second and during the third centuries, spread over the whole of Gaul, preaching the faith and forming churches.  Some went from Lyons at the instigation of St. Irenaeus; others from Rome, especially under the pontificate of Pope St. Fabian, himself martyred in 219; St. Felix and St. Fortunatus to Valence, St. Ferreol to Besancon, St. Marcellus to Chalons-sur-Saone, St. Benignus to Dijon, St. Trophimus to Arles, St. Paul to Narbonne, St. Saturninus to Toulouse, St. Martial to Limoges, St. Andeol and St. Privatus to the Cevennes, St. Austremoine to Clermont-Ferrand, St. Gatian to Tours, St. Denis to Paris, and so many others that their names are scarcely known beyond the pages of erudite historians, or the very spots where they preached, struggled, and conquered, often at the price of their lives.  Such were the founders of the faith and of the Christian Church in France.  At the commencement of the fourth century their work was, if not accomplished, at any rate triumphant; and when, A.D. 312, Constantine declared himself a Christian, he confirmed the fact