Fracture of the Bones.—­The sudden loss of sensation in a foot may cause the animal to use violently the limb he has for months past been carefully nursing.  It may be that the lameness for which the operation has been performed has been due to disease existing in the navicular bone, and extending, perhaps, to the os pedis.  By the disease the bone has already been made brittle, its substance and ligamentous attachments perchance weakened and broken up by a slow-spreading caries, and rarefaction of the remaining bone substance rendered almost certain.  In this instance, the free use of the foot, and the application to the diseased structures of an unwonted pressure immediately after the operation results in fracture.  With the rupture of the structures we get the elevated toe and soft swelling in the heel, as described in gelatinous degeneration.  Treatment, of course, is out of the question.

Neuroma.—­A further sequel is the appearance at the seat of the operation of what is termed an ‘amputational neuroma.’  This is a tumour-like growth occurring on the end of the divided nerve.  It is composed of connective-tissue elements permeated by nerve fibres which have grown out from the axis-cylinders of the nerve stump.  It may vary in size from a pea to a hazel-nut, and is frequently the cause of much pain.  This must be cut down upon and cleanly removed, taking away at the same time as much of the nerve as is possible.

Reunion of the Divided Nerve.—­We may say at once that ‘reunion’ in the popular sense of the word does not take place.  At a varying period after section, however, we do get a return of sensation.  This is brought about in the following manner:  The axis-cylinder of the nerve, still in connection with the spinal cord, swells somewhat, and hypertrophies.  The cells of this hypertrophied portion show a great tendency to proliferate and produce new nerve structure.  This growing point splits, and gives rise to several fibrils, which are new axis-cylinders.  These commence to grow towards the periphery, and, in so doing, grow through the cicatricial tissue that has formed at the seat of the operation.

After passing through the cicatricial tissue (the amount of which tissue, of course, controls the length of time that insensibility remains), the growing axis-cylinders reach the degenerated portions of the nerve below the point of section.  It is along the track of the old nerve that the new growths from the stump reproduce themselves.

The fact of the new growths having to pass through the fibrous tissue of the cicatrix before they can gain the course of the old nerve, along which latter their progress of growth is comparatively easy, affords ample illustration that as large a portion as is possible of the nerve should be removed when operating, in order to convey insensibility for the longest time.  After reunion, of course, nothing remains but to repeat the operation.