But in the first case, as shown by the swelling in the hind legs, if the swelling disappear, and general debility of the system continues; if the eyes grow more drowsy, and discharge from the lower corners; and if this is followed by discharge from the nostrils, slight swelling and hardening of the sub-maxillary glands, which are between the under jaws, then it is clearly developed glanders.  All the glands in the body have now become involved or poisoned, and death must follow in the course of ten or fifteen days, as the constitution of the animal may not be in a condition to combat the disease.

If this disease be annoyed by inoculation from the farcy heads of farcied animals into suppurating sores on other animals, it will be very slow in its progress, especially if it attack the other in a region remote from the lymphatic.  If in a saddle-gall, it will make sores very difficult to heal.  If there is any such thing as checking the disease in its progress, it is in these three cases.

I have observed that when it has been taken in a sore mouth it has followed down the cheek to the sub-maxillary gland, and ended in a clear case of glanders or farcy.  There is another form in which this disease can be taken, and which is, of all others, the most treacherous and dangerous, yet never producing death without the agency of other diseases—­always carrying with it the germs of infection, and ready to convey it to debilitated subjects and cause their death.  The animal will still live himself, and show no sign of disease further than I am about to describe in the position.  It is that which is taken in at the nostrils and attacks the sub-maxillary glands, which become enlarged and will remain so.  When these become overloaded there will be a discharge at the nose.  That being thrown off, it may be some time before any further discharge will be seen from the same source.  In some cases, when the discharge is constant, this can be easily distinguished from gleet or ozena, from the healthy and natural appearance of the membranes of the nose, which at first are pale, then become fiery red or purple.  In gleet the discharges from the nostrils, as in ozena, are of a very light color.  In glanders they are first of a deep yellow, then of a dirty gray—­almost slate color.

Mules affected with glanders of this kind, although it may seem hard from their otherwise healthy appearance, should be destroyed.  They indeed carry with them the germs of infection and death, without any visible marks in their appearance to warn those who have the care of animals against their danger.

Teething.