To give some satisfaction to melancholy men that are troubled with these symptoms, a better means in my judgment cannot be taken, than to show them the causes whence they proceed; not from devils as they suppose, or that they are bewitched or forsaken of God, hear or see, &c. as many of them think, but from natural and inward causes, that so knowing them, they may better avoid the effects, or at least endure them with more patience.  The most grievous and common symptoms are fear and sorrow, and that without a cause to the wisest and discreetest men, in this malady not to be avoided.  The reason why they are so, Aetius discusseth at large, Tetrabib. 2. 2. in his first problem out of Galen, lib. 2. de causis sympt. 1. For Galen imputeth all to the cold that is black, and thinks that the spirits being darkened, and the substance of the brain cloudy and dark, all the objects thereof appear terrible, and the [2660]mind itself, by those dark, obscure, gross fumes, ascending from black humours, is in continual darkness, fear, and sorrow; divers terrible monstrous fictions in a thousand shapes and apparitions occur, with violent passions, by which the brain and fantasy are troubled and eclipsed. [2661]Fracastorius, lib. 2. de intellect, “will have cold to be the cause of fear and sorrow; for such as are cold are ill-disposed to mirth, dull, and heavy, by nature solitary, silent; and not for any inward darkness (as physicians think) for many melancholy men dare boldly be, continue, and walk in the dark, and delight in it:”  solum frigidi timidi:  if they be hot, they are merry; and the more hot, the more furious, and void of fear, as we see in madmen; but this reason holds not, for then no melancholy, proceeding from choler adust, should fear. [2662]Averroes scoffs at Galen for his reasons, and brings five arguments to repel them:  so doth Herc. de Saxonia, Tract. de Melanch. cap. 3. assigning other causes, which are copiously censured and confuted by Aelianus Montaltus, cap. 5 and 6. Lod.  Mercatus de Inter. morb. cur. lib. 1. cap. 17. Altomarus, cap. 7. de mel. Guianerius, tract. 15. c. 1. Bright cap. 37. Laurentius, cap. 5. Valesius, med. cont. lib. 5, con. 1. [2663]"Distemperature,” they conclude, “makes black juice, blackness obscures the spirits, the spirits obscured, cause fear and sorrow.”  Laurentius, cap. 13. supposeth these black fumes offend specially the diaphragma or midriff, and so per consequens the mind, which is obscured as [2664]the sun by a cloud.  To this opinion of Galen, almost all the Greeks and Arabians subscribe, the Latins new and old, internae, tenebrae offuscant animum, ut externae nocent pueris, as children are affrighted in the dark, so are melancholy men at all times, [2665]as having the inward cause with them, and still carrying it about.  Which black vapours, whether they proceed from the black blood about the heart, as T. W. Jes. thinks in his