Unkind, unnatural friends, evil neighbours, bad servants, debts and debates, &c., ’twas Chilon’s sentence, comes aeris alieni et litis est miseria, misery and usury do commonly together; suretyship is the bane of many families, Sponde, praesto noxa est:  “he shall be sore vexed that is surety for a stranger,” Prov. xi. 15, “and he that hateth suretyship is sure.”  Contention, brawling, lawsuits, falling out of neighbours and friends.—­discordia demens (Virg. Aen. 6,) are equal to the first, grieve many a man, and vex his soul. Nihil sane miserabilius eorum mentibus, (as [2375]Boter holds) “nothing so miserable as such men, full of cares, griefs, anxieties, as if they were stabbed with a sharp sword, fear, suspicion, desperation, sorrow, are their ordinary companions.”  Our Welshmen are noted by some of their [2376]own writers, to consume one another in this kind; but whosoever they are that use it, these are their common symptoms, especially if they be convict or overcome, [2377]cast in a suit.  Arius put out of a bishopric by Eustathius, turned heretic, and lived after discontented all his life. [2378]Every repulse is of like nature; heu quanta de spe decidi!  Disgrace, infamy, detraction, will almost effect as much, and that a long time after.  Hipponax, a satirical poet, so vilified and lashed two painters in his iambics, ut ambo laqueo se suffocarent, [2379]Pliny saith, both hanged themselves.  All oppositions, dangers, perplexities, discontents, [2380]to live in any suspense, are of the same rank:  potes hoc sub casu ducere somnos?  Who can be secure in such cases?  Ill-bestowed benefits, ingratitude, unthankful friends, much disquiet and molest some.  Unkind speeches trouble as many; uncivil carriage or dogged answers, weak women above the rest, if they proceed from their surly husbands, are as bitter as gall, and not to be digested.  A glassman’s wife in Basil became melancholy because her husband said he would marry again if she died.  “No cut to unkindness,” as the saying is, a frown and hard speech, ill respect, a browbeating, or bad look, especially to courtiers, or such as attend upon great persons, is present death:  Ingenium vultu statque caditque suo, they ebb and flow with their masters’ favours.  Some persons are at their wits’ ends, if by chance they overshoot themselves, in their ordinary speeches, or actions, which may after turn to their disadvantage or disgrace, or have any secret disclosed.  Ronseus epist. miscel. 2, reports of a gentlewoman 25 years old, that falling foul with one of her gossips, was upbraided with a secret infirmity (no matter what) in public, and so much grieved with it, that she did thereupon solitudines quaerere omnes ab se ablegare, ac tandem in gravissimam incidens melancholiam, contabescere, forsake all company, quite moped, and in a melancholy humour pine away.  Others are as much tortured to see themselves rejected, contemned, scorned, disabled,