Seleucus had an anchor on his thigh, so had his posterity, as Trogus records, lib. 15. Lepidus, in Pliny l. 7. c. 17, was purblind, so was his son.  That famous family of Aenobarbi were known of old, and so surnamed from their red beards; the Austrian lip, and those Indian flat noses are propagated, the Bavarian chin, and goggle eyes amongst the Jews, as [1317] Buxtorfius observes; their voice, pace, gesture, looks, are likewise derived with all the rest of their conditions and infirmities; such a mother, such a daughter; their very [1318]affections Lemnius contends “to follow their seed, and the malice and bad conditions of children are many times wholly to be imputed to their parents;” I need not therefore make any doubt of Melancholy, but that it is an hereditary disease. [1319] Paracelsus in express words affirms it, lib. de morb. amentium to. 4. tr. 1; so doth [1320]Crato in an Epistle of his to Monavius.  So doth Bruno Seidelius in his book de morbo incurab. Montaltus proves, cap. 11, out of Hippocrates and Plutarch, that such hereditary dispositions are frequent, et hanc (inquit) fieri reor ob participatam melancholicam intemperantiam (speaking of a patient) I think he became so by participation of Melancholy.  Daniel Sennertus, lib. 1. part 2. cap. 9, will have his melancholy constitution derived not only from the father to the son, but to the whole family sometimes; Quandoque totis familiis hereditativam, [1321]Forestus, in his medicinal observations, illustrates this point, with an example of a merchant, his patient, that had this infirmity by inheritance; so doth Rodericus a Fonseca, tom. 1. consul. 69, by an instance of a young man that was so affected ex matre melancholica, had a melancholy mother, et victu melancholico, and bad diet together.  Ludovicus Mercatus, a Spanish physician, in that excellent Tract which he hath lately written of hereditary diseases, tom. 2. oper. lib. 5, reckons up leprosy, as those [1322]Galbots in Gascony, hereditary lepers, pox, stone, gout, epilepsy, &c.  Amongst the rest, this and madness after a set time comes to many, which he calls a miraculous thing in nature, and sticks for ever to them as an incurable habit.  And that which is more to be wondered at, it skips in some families the father, and goes to the son, [1323]"or takes every other, and sometimes every third in a lineal descent, and doth not always produce the same, but some like, and a symbolizing disease.”  These secondary causes hence derived, are commonly so powerful, that (as [1324]Wolfius holds) saepe mutant decreta siderum, they do often alter the primary causes, and decrees of the heavens.  For these reasons, belike, the Church and commonwealth, human and Divine laws, have conspired to avoid hereditary diseases, forbidding such marriages as are any whit allied; and as Mercatus adviseth all families to take such, si fieri possit quae maxime distant natura,